Effects of Green and Chemical Cerium Oxides Nanoparticles on the Blood Profile and Liver Enzymes of Cirrhinus mrigala
DOI:
https://doi.org/10.65139/pjzs.v1i1.0024Keywords:
Chemical cerium oxide, green cerium oxide, hematology, liver, nanoparticles, Cirrhinus mrigala, toxicityAbstract
As nanotechnology advances, minute contaminants are increasingly found in both the terrestrial and aquatic environments, raising concerns about nanoparticle pollution such as cerium oxide. They could be consumed by fish and other aquatic life, leading to poisoning, illness, and even death. The goal of the current study was to investigate how cerium oxide nanoparticles physically affected the freshwater Cirrhinus mrigala's liver and hematological markers. Fish for 28 days were exposed to two dosages of each type: 50 mg and 100 mg. The fingerlings in each experimental aquarium were twelve. Following CRD, hepatotoxicity was measured in a spectrophotometer Microlab 300® using the QCA diagnostic kit method for markers such as ALT and AST, alkaline phosphatase (ALP), and total bilirubin. Hematological parameters were evaluated by CBC tests, which included hemoglobin, hematocrit, differential RBCs, WBCs, and platelets. One-way ANOVA was used to statistically examine the data. This study showed that both chemically produced cerium oxide nanoparticles and green cerium oxide had an effect on the liver and blood profile of Cirrhinus mrigala. Histopathological analysis revealed cellular deterioration and necrosis in the liver tissue. Hematological markers like white blood cell counts and hemoglobin levels showed notable variability in the blood profile. These results suggested that both kinds of nanoparticles may have toxicological consequences on fish.
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Copyright (c) 2025 Iqra Aqram, Maryam Riasat, Rida Younas, Naureen Rana, NawazHaider Bashir, Muhmmad Naeem, Huanhuan Chen (Author)
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